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Increased plasma homocysteine concentrations could lead to hyperhomocysteinemia which is a risk factor for several pathologies such as cardiovascular diseases (CVD), and is also related to early atherosclerosis symptoms and venous thrombosis

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Despite these challenges, growing evidence suggests that microbiome-associated metabolic pathways, including bile acid metabolism, short-chain fatty acid production, and tryptophan metabolism, may represent promising targets for therapeutic intervention (118)

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